製品名:(2S)-2-(bromomethyl)oxetane

IUPAC Name:(2S)-2-(bromomethyl)oxetane

CAS番号:2198099-00-0
分子式:C4H7BrO
純度:95%+
カタログ番号:CM422800
分子量:151

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CM422800-100mg in stock ňƏƩ
CM422800-250mg in stock ŭȀƅ
CM422800-500mg in stock ŔȀŔƻ
CM422800-1g in stock ŔƻǕȀ
CM422800-5g in stock șƻŭș

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製品詳細

CAS番号:2198099-00-0
分子式:C4H7BrO
融点:-
SMILESコード:BrC[C@@H]1CCO1
密度:
カタログ番号:CM422800
分子量:151
沸点:
MDL番号:MFCD31926893
保管方法:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.