製品名:(4-Methoxynaphthalen-1-yl)boronic acid

IUPAC Name:(4-methoxynaphthalen-1-yl)boronic acid

CAS番号:219834-95-4
分子式:C11H11BO3
純度:95%
カタログ番号:CM213249
分子量:202.02

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製品詳細

CAS番号:219834-95-4
分子式:C11H11BO3
融点:-
SMILESコード:COC1=C2C=CC=CC2=C(B(O)O)C=C1
密度:
カタログ番号:CM213249
分子量:202.02
沸点:
MDL番号:
保管方法:

Category Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Product Overview (4-methoxynaphthalen-1-yl)boronic acid, also known as 4-MNBA, is a boronic acid derivative of 4-methoxynaphthalene.
Synthesis Method The most commonly used method is the reaction of 4-methoxynaphthalene with boron tribromide in the presence of a base, such as potassium carbonate. This reaction produces (4-methoxynaphthalen-1-yl)boronic Acid and other boronic acid derivatives. Other methods include the reaction of 4-methoxynaphthalene with borane-dimethyl sulfide, the reaction of 4-methoxynaphthalene with boron trifluoride, and the reaction of 4-methoxynaphthalene with boron trichloride in the presence of a base.
Chemical Properties It is relatively inexpensive and easy to obtain, and it is stable and can be stored for long periods of time. It is important to note that (4-methoxynaphthalen-1-yl)boronic Acid is a potentially hazardous material and should be handled with caution.
Synthesis and Application It has been used as a catalyst in the synthesis of compounds, such as 2-aryl-4-methoxynaphthoates and 2-aryl-4-methoxynaphthoic acids. It has also been used as a ligand in the synthesis of organometallic complexes, such as palladium and platinum complexes. In addition, (4-methoxynaphthalen-1-yl)boronic Acid has been used as a reagent in the synthesis of other compounds, such as 1,4-dihydropyridines and 4-methoxynaphthalene-1-sulfonic acids.
Future Directions Further studies on its biochemical and physiological effects could lead to new therapeutic applications. In addition, further research into its mechanism of action could lead to the development of new synthetic methods and catalysts. Finally, (4-methoxynaphthalen-1-yl)boronic Acid could be investigated as a potential reagent for the synthesis of other compounds.