製品名:(3S,4R)-3-amino-4-hydroxy-pyrrolidin-2-one

IUPAC Name:(3S,4R)-3-amino-4-hydroxypyrrolidin-2-one

CAS番号:220812-09-9
分子式:C4H8N2O2
純度:95%+
カタログ番号:CM1018618
分子量:116.12

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製品詳細

CAS番号:220812-09-9
分子式:C4H8N2O2
融点:-
SMILESコード:N[C@@H]1C(=O)NC[C@H]1O
密度:
カタログ番号:CM1018618
分子量:116.12
沸点:
MDL番号:
保管方法:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

VX-147
Vertex Pharmaceuticals announced that inaxaplin (VX-147) , a first-in-class molecule has advanced into the Phase 3 portion of the global Phase 2/3 pivotal clinical trial in APOL1-mediated kidney disease (AMKD), where a 45 mg once daily oral dose will be compared to placebo, on top of standard of care. The clinical trial is designed to assess the impact of inaxaplin on kidney function and proteinuria for people living with proteinuric kidney disease mediated by two variants in the APOL1 gene, known as AMKD. In addition, the trial has been expanded to include adolescents with AMKD ages 10 to 17 years.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.