製品名:6-chloro-3-iodo-1-tetrahydropyran-2-yl-pyrazolo[3,4-b]pyrazine

IUPAC Name:6-chloro-3-iodo-1-(oxan-2-yl)-1H-pyrazolo[3,4-b]pyrazine

CAS番号:2215028-64-9
分子式:C10H10ClIN4O
純度:95%+
カタログ番号:CM479274
分子量:364.57

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製品詳細

CAS番号:2215028-64-9
分子式:C10H10ClIN4O
融点:-
SMILESコード:ClC1=CN=C2C(I)=NN(C3CCCCO3)C2=N1
密度:
カタログ番号:CM479274
分子量:364.57
沸点:
MDL番号:MFCD32220431
保管方法:

Category Infos

Pyrazolopyrazines
The pyrazolopyrazine ring system is a very interesting class of heterocyclic compounds considered as important scaffolds for many effective bioactive agents with low toxicity, antioxidant, anticonvulsant, antiparasitic, anti-inflammatory, antiviral, antibacterial, anti- Fungal and analgesic activity.

Column Infos

GDC-1971
Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.

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