製品名:1-cyclopropanecarbonyl-6-fluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid

IUPAC Name:1-cyclopropanecarbonyl-6-fluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid

CAS番号:2248830-82-0
分子式:C14H14FNO3
純度:95%+
カタログ番号:CM1030825
分子量:263.27

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製品詳細

CAS番号:2248830-82-0
分子式:C14H14FNO3
融点:-
SMILESコード:OC(=O)C1CN(C(=O)C2CC2)C2=CC=C(F)C=C2C1
密度:
カタログ番号:CM1030825
分子量:263.27
沸点:
MDL番号:
保管方法:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Tetrahydroquinolines
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, widely found in nature and in a variety of pharmacologically active compounds. Tetrahydroquinoline is an important structure for the synthesis of various biologically active derivatives.

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