製品名:(2S,4R)-1-[(2S)-2-[6-[[2-[2,3-difluoro-6-(2-morpholinothiazol-4-yl)phenoxy]acetyl]amino]hexanoylamino]-3,3-dimethyl-butanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methylthiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

IUPAC Name:(2S,4R)-1-[(2S)-2-[6-(2-{2,3-difluoro-6-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]phenoxy}acetamido)hexanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

CAS番号:2488296-78-0
分子式:C44H55F2N7O7S2
純度:97%
カタログ番号:CM1076148
分子量:896.08

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CM1076148-100mg in stock ǤŹŹǵ

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製品詳細

CAS番号:2488296-78-0
分子式:C44H55F2N7O7S2
融点:-
SMILESコード:C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCNC(=O)COC1=C(C=CC(F)=C1F)C1=CSC(=N1)N1CCOCC1)C(C)(C)C)C1=CC=C(C=C1)C1=C(C)N=CS1
密度:
カタログ番号:CM1076148
分子量:896.08
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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