製品名:2-{3-[(2,4-dioxo-1,3-diazinan-1-yl)methyl]-2-oxo-1,2-dihydropyridin-1-yl}acetaldehyde

IUPAC Name:2-{3-[(2,4-dioxo-1,3-diazinan-1-yl)methyl]-2-oxo-1,2-dihydropyridin-1-yl}acetaldehyde

CAS番号:2633633-40-4
分子式:C12H13N3O4
純度:95%+
カタログ番号:CM1046115
分子量:263.25

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製品詳細

CAS番号:2633633-40-4
分子式:C12H13N3O4
融点:-
SMILESコード:O=CCN1C=CC=C(CN2CCC(=O)NC2=O)C1=O
密度:
カタログ番号:CM1046115
分子量:263.25
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

Column Infos

E3 ligase ligand
E3 ligase ligand is an important biochemical molecule, which plays an important role in cells. It can bind to E3 ligase, thus promoting protein degradation and cell metabolism. In vivo, the stability and activity of E3 ligase ligands are very important for the normal function of cells. Studies have shown that E3 ligase ligands play an important role in cell cycle, apoptosis, DNA repair and other aspects.

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