製品名:N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]-7-(hydroxyamino)-7-oxo-heptanamide

IUPAC Name:N'-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]-N-hydroxyheptanediamide

CAS番号:2758388-35-9
分子式:C20H24N4O6
純度:95%
カタログ番号:CM1077510
分子量:416.43

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製品詳細

CAS番号:2758388-35-9
分子式:C20H24N4O6
融点:-
SMILESコード:ONC(=O)CCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
密度:
カタログ番号:CM1077510
分子量:416.43
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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