製品名:6-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-carbazole

IUPAC Name:6-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-carbazole

CAS番号:2805-84-7
分子式:C13H12F3N
純度:95%+
カタログ番号:CM132983
分子量:239.24

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製品詳細

CAS番号:2805-84-7
分子式:C13H12F3N
融点:-
SMILESコード:FC(C1=CC2=C(NC3=C2CCCC3)C=C1)(F)F
密度:
カタログ番号:CM132983
分子量:239.24
沸点:331.4°C at 760 mmHg
MDL番号:MFCD09259265
保管方法:Store at room temperature.

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Carbazoles
Carbazoles are an important class of nitrogen-containing heterocycles with a planar tricyclic skeleton consisting of two benzene rings fused on both sides of the central pyrrole ring, with a large aromatic system and a central nitrogen atom, showing broad of electron delocalization. The structure of this compound is based on the indole structure, but in which a second benzene ring is fused to a five-membered ring at positions 2-3 of the indole. Carbazole structural motifs are widely found in, but not limited to, a large number of natural alkaloids of plant or bacterial origin. Since many of these alkaloids are medically useful, exhibit a fairly wide range of biological activities (anticancer, anti-HIV, antibacterial, anti-Alzheimer's disease, anticoagulant, analgesic, antiepileptic, antidiabetic, antioxidant, etc.). Medicinal chemistry also uses carbazole motifs in synthetic drugs to combat hypertension, heart disease, and hepatitis C virus replication.
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Column Infos

Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.

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