製品名:1-(4-bromo-2,6-dimethyl-phenyl)-3-(2-trimethylsilylethoxymethyl)hexahydropyrimidine-2,4-dione

IUPAC Name:1-(4-bromo-2,6-dimethylphenyl)-3-{[2-(trimethylsilyl)ethoxy]methyl}-1,3-diazinane-2,4-dione

CAS番号:2940949-09-5
分子式:C18H27BrN2O3Si
純度:95%
カタログ番号:CM1076486
分子量:427.41

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製品詳細

CAS番号:2940949-09-5
分子式:C18H27BrN2O3Si
融点:-
SMILESコード:CC1=CC(Br)=CC(C)=C1N1CCC(=O)N(COCC[Si](C)(C)C)C1=O
密度:
カタログ番号:CM1076486
分子量:427.41
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.