製品名:2,4-dichloropyrimidine-5-carbonyl chloride

IUPAC Name:2,4-dichloropyrimidine-5-carbonyl chloride

CAS番号:2972-52-3
分子式:C5HCl3N2O
純度:95%+
カタログ番号:CM100730
分子量:211.43

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製品詳細

CAS番号:2972-52-3
分子式:C5HCl3N2O
融点:-
SMILESコード:O=C(Cl)C1=CN=C(Cl)N=C1Cl
密度:1.675g/cm3
カタログ番号:CM100730
分子量:211.43
沸点:304.3°C at 760 mmHg
MDL番号:MFCD09742432
保管方法:Store at 2-8°C.

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Cerdulatinib
Cerdulatinib is a small molecule SYK/JAK kinase inhibitor in development for treatment of hematological malignancies. It has lowest nM IC50 values against TYK2, JAK1, JAK2, JAK3, FMS, and SYK. Cerdulatinib is a reversible ATP-competitive dual JAK and Syk inhibitor. The FDA granted orphan drug status to cerdulatinib for the treatment of peripheral T-cell lymphoma (PTCL).

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