cas 309915-46-6|| where to buy (2R,5S)-1-Boc-2,5-dimethyl-piperazine

製品名:(2R,5S)-1-Boc-2,5-dimethyl-piperazine

IUPAC Name:tert-butyl (2R,5S)-2,5-dimethylpiperazine-1-carboxylate

: CAS番号：309915-46-6; 分子式：C11H22N2O2; 純度：98%

: カタログ番号：CM169834; 分子量：214.31

包装単位	有効在庫	価格（USD）
CM169834-10g	in stock	ǲȌ
CM169834-25g	in stock	ǕſƋ
CM169834-100g	in stock	ſƱſ

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製品詳細

: CAS番号:309915-46-6; 分子式:C11H22N2O2; 融点:-; SMILESコード:O=C(N1[C@H](C)CN[C@@H](C)C1)OC(C)(C)C; 密度:

: カタログ番号:CM169834; 分子量:214.31; 沸点:280°C at 760 mmHg; MDL番号:MFCD06797728; 保管方法:Store at 2-8°C.

Category Infos

: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

Column Infos

: MK-1084; Merck initiates Phase 3 clinical trial of MK-1084, an investigational oral KRAS G12C inhibitor, in combination with KEYTRUDA® (pembrolizumab) for first-line treatment of certain patients with metastatic non-small cell lung cancer. KRAS mutations are one of the most frequently observed mutations in human cancers, making them a crucial target for precision oncology therapy.
MK-1084 is an investigational, oral covalent inhibitor of KRAS G12C, that is found in about 14% of people with non-small cell lung cancer. MK-1084 is currently under Phase 1 evaluation as monotherapy and as combined therapies in patients with KRAS G12C mutant advanced solid tumors.

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