製品名:(R)-3-Boc-AMinopiperidine

IUPAC Name:tert-butyl N-[(3R)-piperidin-3-yl]carbamate

CAS番号:309956-78-3
分子式:C10H20N2O2
純度:97%
カタログ番号:CM101941
分子量:200.28

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製品詳細

CAS番号:309956-78-3
分子式:C10H20N2O2
融点:-
SMILESコード:O=C(N[C@H]1CNCCC1)OC(C)(C)C
密度:
カタログ番号:CM101941
分子量:200.28
沸点:
MDL番号:MFCD03093382
保管方法:Store at room temperature.

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Column Infos

BMF-219
Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.
JNT-517
Jnana Therapeutics announced positive, statistically significant interim results from its ongoing clinical study of JNT-517 in individuals with phenylketonuria (PKU). JNT-517, a small molecule inhibitor of the phenylalanine (Phe) transporter SLC6A19, is being evaluated as a potential first-in-class oral treatment for PKU across all ages and genotypes. Based on these positive mid-term results, Jnana has adjusted its phase 1b clinical trial design to support the critical phase 3 clinical trial of JNT-517 starting in the first half of 2025.
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