製品名:4-chloro-7H-pyrrolo[2,3-d]pyrimidine

IUPAC Name:4-chloro-7H-pyrrolo[2,3-d]pyrimidine

CAS番号:3680-69-1
分子式:C6H4ClN3
純度:95%+
カタログ番号:CM101908
分子量:153.57

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CM101908-500g in stock źȎư

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製品詳細

CAS番号:3680-69-1
分子式:C6H4ClN3
融点:-
SMILESコード:ClC1=C2C=CNC2=NC=N1
密度:
カタログ番号:CM101908
分子量:153.57
沸点:325.9°C at 760 mmHg
MDL番号:MFCD01686865
保管方法:Keep in a dry and a tight container and store at ambient temperature

Category Infos

Pyrrolopyrimidines
Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.

Column Infos

Delgocitinib
Positive phase 3 head-to-head data results from DELTA FORCE trial comparing delgocitinib cream with alitretinoin capsules in adults with severe chronic hand eczema (CHE). Delgocitinib cream demonstrated a superior reduction in Hand Eczema Severity Index score from baseline to Week 12 compared to alitretinoin capsules as its primary outcome measure.
Delgocitinib cream is an investigational, first-in-class, topical pan-Janus kinase (JAK) inhibitor for CHE. It inhibits the activation of JAK-STAT signaling, which plays a key role in the pathogenesis of CHE.