製品名:methyl 20-hydroxyicosanoate
IUPAC Name:methyl 20-hydroxyicosanoate
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| Product Overview |
Methyl 20-hydroxyeicosanoate (20-HETE) is a highly bioactive fatty acid derived from the metabolism of arachidonic acid. It is an important signaling molecule that plays an important role in the regulation of systemic and local physiological processes, including inflammation, vascular tone, and cell proliferation. |
| Synthesis Method |
Methyl 20-hydroxyeicosanoate is synthesized by the action of two enzymes, cytochrome P450 (CYP) 4A11 and CYP4F2, which are found in the endoplasmic reticulum of cells. The synthesis of Methyl 20-hydroxyeicosanoate involves the oxidation of arachidonic acid by CYP4A11, followed by the hydroxylation of the 20-carbon position by CYP4F2. The resulting product is Methyl 20-hydroxyeicosanoate, which is then released from the cell and can act on a variety of different cellular targets. |
| Chemical Properties |
Methyl 20-hydroxyeicosanoate has a short half-life, which can make it difficult to study its effects over a prolonged period of time. In addition, methyl 20-hydroxyeicosanoate has been found to be highly reactive, which can make it difficult to control the concentration of the molecule in the laboratory. |
| Synthesis and Application |
Methyl 20-hydroxyeicosanoate has been shown to play a role in the regulation of systemic and local physiological processes, including inflammation, vascular tone, and cell proliferation. Furthermore, Methyl 20-hydroxyeicosanoate has been studied in the context of cancer, cardiovascular disease, and metabolic disorders, and has been found to be involved in the regulation of these conditions. |
| Future Directions |
First, further research is needed to better understand the mechanism of action of Methyl 20-hydroxyeicosanoate and its effects on different cellular targets. Second, further research is needed to explore the potential therapeutic applications of Methyl 20-hydroxyeicosanoate, including its potential use in the treatment of cancer, cardiovascular disease, and metabolic disorders. Third, further research is needed to explore the potential use of Methyl 20-hydroxyeicosanoate as a biomarker for disease progression and treatment efficacy. Finally, further research is needed to explore the potential use of Methyl 20-hydroxyeicosanoate as a tool for diagnosing and monitoring diseases, such as cancer and cardiovascular disease. |
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