製品名:4-Amino-6-chloro-5-hydroxypyrimidine

IUPAC Name:4-amino-6-chloropyrimidin-5-ol

CAS番号:38953-42-3
分子式:C4H4ClN3O
純度:95%+
カタログ番号:CM116619
分子量:145.55

包装単位 有効在庫 価格(USD) 数量
CM116619-100mg in stock ȋƅ
CM116619-250mg in stock şœ
CM116619-1g in stock ƏǠǺ
CM116619-5g in stock ȋǠş

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製品詳細

CAS番号:38953-42-3
分子式:C4H4ClN3O
融点:-
SMILESコード:OC1=C(Cl)N=CN=C1N
密度:
カタログ番号:CM116619
分子量:145.55
沸点:312.5°C at 760 mmHg
MDL番号:MFCD13689013
保管方法:Store at room temperature

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Remibrutinib
Novartis announced new positive data from the Phase III REMIX-1 and REMIX-2 studies investigating remibrutinib - a highly selective, oral Bruton's tyrosine kinase (BTK) inhibitor - in people with chronic spontaneous urticaria (CSU) whose symptoms are inadequately controlled by H1-antihistamines. In the studies, remibrutinib met all primary and secondary endpoints at Week 12. Remibrutinib is a potential 'best-in-class' BTK inhibitor. It can covalently bind to the BTK enzyme of B cells and myeloid cells. While strongly inhibiting BTK activity, it reduces the systemic exposure of the drug and reduces the risk of adverse events and drug interactions.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.