製品名:Methyl 2-amino-2-(oxetan-3-yl)acetate

IUPAC Name:methyl 2-amino-2-(oxetan-3-yl)acetate

CAS番号:394653-40-8
分子式:C6H11NO3
純度:90%+
カタログ番号:CM200558
分子量:145.16

包装単位 有効在庫 価格(USD) 数量
CM200558-250mg in stock ȎNJǵ
CM200558-1g in stock ưƞȎ
CM200558-5g in stock ʼnʼnźź

研究開発用専用.

問い合わせフォーム

   refresh    

製品詳細

CAS番号:394653-40-8
分子式:C6H11NO3
融点:-
SMILESコード:O=C(OC)C(N)C1COC1
密度:
カタログ番号:CM200558
分子量:145.16
沸点:201.4°C at 760 mmHg
MDL番号:MFCD18849135
保管方法:Store at 2-8°C.

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.