製品名:1-(5-Nitrothiophen-2-yl)ethanone
IUPAC Name:1-(5-nitrothiophen-2-yl)ethan-1-one
Product Overview |
2-Acetyl-5-nitrothiophene (2-AN) is a synthetic, organic compound with a wide range of biological applications. It is an aromatic heterocyclic compound, which is composed of a five-membered ring containing two carbon atoms, one nitrogen atom and two sulfur atoms. |
Synthesis Method |
The most common method involves the reaction of 5-nitrothiophene-2-carboxylic acid with an amine, such as aniline, in the presence of a base. The reaction produces 2-Acetyl-5-nitrothiophene and an amide byproduct. Other methods of synthesis include the reaction of 5-nitrothiophene-2-carboxylic acid with an alcohol or aldehyde in the presence of a base, or the reaction of 5-nitrothiophene-2-carboxylic acid with an acid chloride in the presence of a base. |
Chemical Properties |
One of the main advantages is that it is relatively inexpensive and easy to synthesize. Additionally, it has a wide range of biological activities. However, 2-Acetyl-5-nitrothiophene is also limited by its low solubility in aqueous solutions and its instability in the presence of light and heat. |
Synthesis and Application |
2-Acetyl-5-nitrothiophene is widely used as a research tool in biochemistry and physiology. In vivo and in vitro studies have been conducted to investigate the biological activities of 2-Acetyl-5-nitrothiophene. In vivo studies involve the administration of 2-Acetyl-5-nitrothiophene to animals or humans to observe its effects on the body. In vitro studies involve the use of cell cultures or isolated enzymes to study the effects of 2-Acetyl-5-nitrothiophene on biochemical or physiological processes. |
Future Directions |
Further investigations into the mechanism of action of 2-Acetyl-5-nitrothiophene and its potential therapeutic applications. Development of new synthetic methods for the synthesis of 2-Acetyl-5-nitrothiophene. Development of new derivatives of 2-Acetyl-5-nitrothiophene with improved pharmacokinetic properties.Investigation of the potential of 2-Acetyl-5-nitrothiophene as an anticancer agent. |