製品名:4-Chloro-2-methoxy-1-methylbenzene

IUPAC Name:4-chloro-2-methoxy-1-methylbenzene

CAS番号:40794-04-5
分子式:C8H9ClO
純度:97%
カタログ番号:CM283380
分子量:156.61

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製品詳細

CAS番号:40794-04-5
分子式:C8H9ClO
融点:-
SMILESコード:CC1=CC=C(Cl)C=C1OC
密度:
カタログ番号:CM283380
分子量:156.61
沸点:204°C at 760 mmHg
MDL番号:MFCD07368289
保管方法:Store at 2-8°C.

Column Infos

Crinecerfont
The New England Journal of Medicine publishes the primary CAHtalyst™ Adult Phase 3 study results of Crinecerfont for the treatment of congenital adrenal hyperplasia (CAH). Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is a rare genetic disorder, affected by a lack of cortisol and/or aldosterone. Corticotropin-releasing factor type 1 receptor (CRF1) antagonism is shown to clinically decrease ACTH production and adrenal androgen levels.
Neurocrine's Crinecerfont is an investigational, selective CRF1 antagonist being developed to reduce and control excess adrenocorticotropic hormone (ACTH) and adrenal androgens. The phase 3 study meets primary and important key secondary endpoints, including a significant reduction in androstenedione levels and lowering glucocorticoid dosing.