cas 42754-96-1|| where to buy 4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

製品名:4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

IUPAC Name:4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

包装単位	有効在庫	価格（USD）
CM104106-5g	in stock	Ţư
CM104106-25g	in stock	Ľŉŉ
CM104106-100g	in stock	źĽŉ

研究開発用専用.

問い合わせフォーム

化学物質名

CAS番号

数量*

要求仕様*
（アッセイ %、材料グレード等）

お名前*

連絡先Eメールアドレス*

Meanwhile I'd like to create a registered account on CHEMENU.COM with the above email.

I'd like to receive emails related to products with similar structures to 42754-96-1 regularly via the above email.

追記事項

Verification code*

refresh

: CAS番号:42754-96-1; 分子式:C5H2Cl2N4; 融点:-; SMILESコード:ClC1=NC(Cl)=C2C=NNC2=N1; 密度:

: カタログ番号:CM104106; 分子量:189; 沸点:; MDL番号:MFCD09835493; 保管方法:Keep in inert atmosphere, store at 2-8°C.

: Pyrazolopyrimidines; Pyrazolopyrimidine scaffolds are one of the most important heterocyclic compounds in drug discovery. This scaffold has various biological activities, among which anticancer is an important one.

: ORIC-533; ORIC-533 is a potential best-in-class, oral inhibitor of CD73 developed by ORIC Pharmaceuticals which is currently in a Ph. Ib trial for the treatment of relapsed/refractory multiple myeloma (MM). It inhibits the CD73-mediated conversion of AMP to adenosine which generates an immunosuppressive tumor microenvironment and has the potential to be a next-generation immunotherapy. The in-depth use of co-crystal structures led the team to discover a novel set of phosphonate bioisosteres which were able to achieve bioavailability for a highly polar scaffold. The structure and discovery story of ORIC-533 were recently presented at the ACS Spring 2024 Meeting in New Orleans.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.