cas 55750-63-5|| where to buy 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)

製品名:6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)

IUPAC Name:2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate

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CM328887-50mg	in stock	ɐǆ
CM328887-100mg	in stock	ƼƋ
CM328887-500mg	in stock	ȷſƋ

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: CAS番号:55750-63-5; 分子式:C14H16N2O6; 融点:-; SMILESコード:O=C(ON1C(CCC1=O)=O)CCCCCN2C(C=CC2=O)=O; 密度:

: カタログ番号:CM328887; 分子量:308.29; 沸点:480.6°C at 760 mmHg; MDL番号:MFCD00043043; 保管方法:

: Pyrrolidines; Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

: Pyrrolines; Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.

: ADC-Linkers; The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.

: Maleimides; Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.

: Non-cleavable linkers; Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.