製品名:3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazole

IUPAC Name:3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazole

CAS番号:59074-26-9
分子式:C15H13ClN2
純度:95%
カタログ番号:CM126738
分子量:256.73

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製品詳細

CAS番号:59074-26-9
分子式:C15H13ClN2
融点:-
SMILESコード:ClC1=CC=C(C2=NNCC2C3=CC=CC=C3)C=C1
密度:
カタログ番号:CM126738
分子量:256.73
沸点:393°C at 760 mmHg
MDL番号:MFCD07776855
保管方法:Store at 2-8°C.

Category Infos

Pyrazolines
Pyrazoline is a heterocyclic chemical compound with the molecular formula C3H6N2. Pyrazolines are well-known and important nitrogen-containing five-membered ring heterocyclic compounds. Pyrazoline derivatives have numerous prominent pharmacological effects, such as antimicrobial, anti-inflammatory, analgesic, antidepressant and anticancer.

Column Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
Monlunabant
Obesity is linked to overactivity of the endocannabinoid system that regulates appetite, fat storage, and insulin resistance. Cannabinoid receptor type-1 (CB1) belongs to the G protein-coupled receptor (GPCR) superfamily, and are found in the brain and peripheral tissues. Pharmacological blockers of CB1 receptors have demonstrated effectiveness in suppressing appetite, inducing weight loss, enhancing energy expenditure and speeding up metabolism.
Novo Nordisk’s Monlunabant is a novel peripherally-acting CB1 receptor blocker. This target limits brain penetration and minimizes psychiatric side-effects. Monlunabant is developed for the treatment of metabolic disorders. The phase 2 trials for diabetic kidney disease and obesity is expected in the second half of 2024.

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