製品名:2-(1-hydroxy-3-oxoisoindolin-2-yl)benzoic acid
IUPAC Name:2-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid
Product Overview |
2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid, also known as HOBt, is a chemical compound commonly used in organic chemistry as a coupling reagent. HOBt is widely used in peptide synthesis and other organic reactions due to its high reactivity and stability. |
Physical Properties |
2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid is a white crystalline powder that is soluble in water and organic solvents. |
Chemical Properties |
2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid is often utilized as a a coupling reagent in organic chemistry. |
Synthesis and Application |
2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid is widely used in peptide synthesis as a coupling reagent. It is used to activate carboxylic acids for the formation of amide bonds with amino acids. 2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid is also used in the synthesis of other organic compounds such as esters, lactones, and hydrazides. 2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid has been used in the synthesis of various natural products and pharmaceuticals. |
Storage and Handling |
Store 2-(1-Hydroxy-3-oxoisoindolin-2-yl)benzoic acid at 2-8°C. |