製品名:3-hydroxy-4-{2-methylimidazo[1,2-a]pyridine-3-carbonyl}-1-[2-(morpholin-4-yl)ethyl]-5-(pyridin-3-yl)-2,5-dihydro-1H-pyrrol-2-one

IUPAC Name:3-hydroxy-4-{2-methylimidazo[1,2-a]pyridine-3-carbonyl}-1-[2-(morpholin-4-yl)ethyl]-5-(pyridin-3-yl)-2,5-dihydro-1H-pyrrol-2-one

CAS番号:630064-04-9
分子式:C24H25N5O4
純度:95%+
カタログ番号:CM627000
分子量:447.5

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製品詳細

CAS番号:630064-04-9
分子式:C24H25N5O4
融点:-
SMILESコード:CC1=C(N2C=CC=CC2=N1)C(=O)C1=C(O)C(=O)N(CCN2CCOCC2)C1C1=CC=CN=C1
密度:
カタログ番号:CM627000
分子量:447.5
沸点:
MDL番号:
保管方法:

Category Infos

Morpholines
Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.