製品名:8-benzyl-8-azaspiro[bicyclo[3.2.1]octane-3,4'-imidazolidine]-2',5'-dione

IUPAC Name:8-benzyl-8-azaspiro[bicyclo[3.2.1]octane-3,4'-imidazolidine]-2',5'-dione

CAS番号:64192-79-6
分子式:C16H19N3O2
純度:95%
カタログ番号:CM138923
分子量:285.35

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製品詳細

CAS番号:64192-79-6
分子式:C16H19N3O2
融点:-
SMILESコード:O=C1NC2(C(N1)=O)CC(N3CC4=CC=CC=C4)CCC3C2
密度:
カタログ番号:CM138923
分子量:285.35
沸点:
MDL番号:
保管方法:Store at 2-8°C.

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Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Imidazolidines
Imidazolidine is a heterocyclic compound (CH2)2(NH)2CH2. The parental imidazolidines are less studied, but related compounds substituted on one or both nitrogen centers are more common. Generally, they are colorless, polar, basic compounds. Imidazolidines are examples of cyclic 5-membered general amines. Imidazolidine derivatives are key components in the development of bioactive compounds for the treatment of various diseases, especially Chagas disease. In fact, other studies have shown that imidazoline-2,4-diones have a wide range of pharmacological activities, including anticonvulsant, antiarrhythmic, and antiparasitic.
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