cas 676371-65-6|| where to buy methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate hydrochloride

製品名:methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate hydrochloride

IUPAC Name:methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate hydrochloride

包装単位	有効在庫	価格（USD）
CM108439-1g	in stock	ŮŌǙ
CM108439-5g	in stock	ǙǙľ

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: CAS番号:676371-65-6; 分子式:C7H12ClNO2; 融点:-; SMILESコード:O=C(C1(C2)CC2(N)C1)OC.[H]Cl; 密度:

: Bridged Compounds; Bridged ring compound refers to any two rings in the compound, which share two non-directly connected carbon atoms, and are classified into bicyclic hydrocarbons, tricyclic hydrocarbons, tetracyclic hydrocarbons, etc. Carbon atoms used in two or more rings are bridgehead carbon atoms, and the bond connecting the bridgehead carbon atoms is called a bridge. Bridged ring compounds are a class of organic compounds that are widely present in nature and usually have important physiological activities, such as the famous anticancer drug paclitaxel and antimalarial drug artemisinin.; bridged compounds,bridged bicyclic compounds; Buy low price, high quality bridged compounds and bridged bicyclic compounds,choose our products,Chemenu is the leading factory & company. Warmly welcome new and old customers to visit and patronize!

: Cyclobutanes; The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.

: DNL343; Denali Therapeutics announces completion of enrollment for regimen G evaluating eIF2B agonist DNL343 in the phase 2/3 HEALEY ALS platform trial. Amyotrophic lateral sclerosis (ALS) causes progressive nerve degeneration in the spinal cord and brain, representing a large unmet medical need. The activation of integrated stress response (ISR) is documented in ALS patients, resulting in the suppression of eukaryotic translation initiation factor 2B (eIF2B) activity, and impaired protein synthesis.
Denali's ALS therapy DNL343 is an investigational small molecule eIF2B activator. It is designed to restore protein synthesis and inhibit ISR pathway in ALS. The compound is found to be generally well-tolerated and support once-daily dosing.