cas 6966-01-4|| where to buy methyl 3-amino-6-bromopyrazine-2-carboxylate

製品名:methyl 3-amino-6-bromopyrazine-2-carboxylate

IUPAC Name:methyl 3-amino-6-bromopyrazine-2-carboxylate

: CAS番号：6966-01-4; 分子式：C6H6BrN3O2; 純度：95%+

: カタログ番号：CM102385; 分子量：232.04

包装単位	有効在庫	価格（USD）
CM102385-100g	in stock	ưƀƦ
CM102385-500g	in stock	ŴƎɅ

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製品詳細

: CAS番号:6966-01-4; 分子式:C6H6BrN3O2; 融点:-; SMILESコード:O=C(C1=NC(Br)=CN=C1N)OC; 密度:

: カタログ番号:CM102385; 分子量:232.04; 沸点:322.4°C at 760 mmHg; MDL番号:MFCD00834964; 保管方法:Keep in dark place, store at 2-8°C.

Category Infos

: Pyrazines; Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.; pyrazine,pyrazine price; if you want to know the latest news about pyrazine and pyrazine price, please come to our website and get a quote for free.

Column Infos

: Pyrazines

: Darovasertib; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Darovasertib, a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma”. Uveal melanoma (UM) is the most common primary intraocular malignancy. About half of primary uveal melanoma tumors metastasize but with no standard treatment. Most patients with metastatic uveal melanoma have been found to have mutations in GNAQ or GNA11, that are associated with consistent activation of the protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) pathways.
IDEAYA's Darovasertib (IDE196) is a potent, selective small molecule inhibitor of PKC which stops activating PKC/MEK pathway. Darovasertib is under Phase 2 expansion and Phase 3 registrational trial with Crizotinib in GNAQ/11 metastatic cutaneous melanoma.

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