cas 72141-41-4|| where to buy (4-nitrophenyl)-piperazin-1-yl-methanone

製品名:(4-nitrophenyl)-piperazin-1-yl-methanone

IUPAC Name:1-(4-nitrobenzoyl)piperazine

: CAS番号：72141-41-4; 分子式：C11H13N3O3; 純度：95%+

: カタログ番号：CM388879; 分子量：235.24

包装単位	有効在庫	価格（USD）
CM388879-1g	in stock	ǜȺ
CM388879-5g	in stock	ǶŵȺ

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製品詳細

: CAS番号:72141-41-4; 分子式:C11H13N3O3; 融点:-; SMILESコード:O=[N+]([O-])C1=CC=C(C=C1)C(=O)N2CCNCC2; 密度:

: カタログ番号:CM388879; 分子量:235.24; 沸点:; MDL番号:; 保管方法:

Category Infos

: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

Column Infos

: Mitapivat; Jan. 03 2024, Agios announces Phase 3 ENERGIZE study of PYRUKYND (Mitapivat) met primary endpoint and both key secondary endpoints in adults with non-transfusion-dependent(NTD) alpha- or beta-thalassemia. The positive data showed Mitapivat’s potential to become the first oral therapy approved for NTD thalassemia.
Mitapivat is a pyruvate kinase activator indicated for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency in the US, and for the treatment of PK deficiency in adult patients in the EU. By activating and stabilizing mutant pyruvate kinase, Mitapivat targets the underlying enzymatic defect that causes chronic hemolysis and ineffective erythropoiesis in order to restore enzyme activity.

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