Aziridines are highly strained three-membered heterocyclic molecules composed of one amine group and two carbon units. They are aza analogs of epoxides. Aziridines are a very important class of synthetic building blocks and intermediates in organic synthesis, which are widely used in organic synthesis, especially in the synthesis of nitrogen-containing natural products. Due to the high ring tension of aziridine, its reactivity is high. Under certain conditions, it can undergo cycloaddition reaction with various dipolar reagents to prepare some new nitrogen-containing heterocyclic compounds.
Aziridines are a very important class of synthetic building blocks and intermediates in organic synthesis
Aziridines,
Aziridines are highly strained three-membered heterocyclic molecules composed of one amine group and two carbon units. They are aza analogs of epoxides.
Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.
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