製品名:8-(Benzyloxy)-N-(4-((3-methyloxetan-3-yl)methoxy)-2-nitrophenyl)quinolin-2-amine

IUPAC Name:8-(benzyloxy)-N-{4-[(3-methyloxetan-3-yl)methoxy]-2-nitrophenyl}quinolin-2-amine

CAS番号:816463-37-3
分子式:C27H25N3O5
純度:97%
カタログ番号:CM227306
分子量:471.51

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製品詳細

CAS番号:816463-37-3
分子式:C27H25N3O5
融点:-
SMILESコード:O=[N+](C1=CC(OCC2(C)COC2)=CC=C1NC3=NC4=C(OCC5=CC=CC=C5)C=CC=C4C=C3)[O-]
密度:
カタログ番号:CM227306
分子量:471.51
沸点:
MDL番号:MFCD12973805
保管方法:

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.