製品名:Grantaline

IUPAC Name:(1R,4R,7R,8R,18R)-8-hydroxy-5,5,7,8-tetramethyl-2,6,10-trioxa-15-azatetracyclo[10.5.1.0⁴,⁷.0¹⁵,¹⁸]octadec-12-ene-3,9-dione

CAS番号:83482-61-5
分子式:C18H25NO6
純度:95%+
カタログ番号:CM599584
分子量:351.4

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製品詳細

CAS番号:83482-61-5
分子式:C18H25NO6
融点:-
SMILESコード:CC1(C)O[C@]2(C)[C@@H]1C(=O)O[C@@H]1CCN3CC=C(COC(=O)[C@]2(C)O)[C@H]13
密度:
カタログ番号:CM599584
分子量:351.4
沸点:
MDL番号:
保管方法:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.
Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.

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