cas 844870-83-3|| where to buy 6-Chloro-2-((1-(2,2-difluoroethyl)-5-(methylsulfonyl)-1H-pyrazol-3-yl)methyl)-4-phenyl-3-propionylisoquinolin-1(2H)-one

製品名:6-Chloro-2-((1-(2,2-difluoroethyl)-5-(methylsulfonyl)-1H-pyrazol-3-yl)methyl)-4-phenyl-3-propionylisoquinolin-1(2H)-one

IUPAC Name:6-chloro-2-{[1-(2,2-difluoroethyl)-5-methanesulfonyl-1H-pyrazol-3-yl]methyl}-4-phenyl-3-propanoyl-1,2-dihydroisoquinolin-1-one

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: CAS番号:844870-83-3; 分子式:C25H22ClF2N3O4S; 融点:-; SMILESコード:O=C1N(CC2=NN(CC(F)F)C(S(=O)(C)=O)=C2)C(C(CC)=O)=C(C3=CC=CC=C3)C4=C1C=CC(Cl)=C4; 密度:

: カタログ番号:CM224929; 分子量:533.97; 沸点:; MDL番号:; 保管方法:Store at 2-8°C.

: Pyrazoles; Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.; Pyrazone; Custom pyrazone for customers from all over the world are our main business.

: Fluorinated Compounds; Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

: Isoquinolines; Compared to quinolines, isoquinolines are also prominent structural motifs present in many biologically significant natural and synthetic compounds. Some well-known isoquinoline alkaloids include the anticancer and anticonvulsant berberine, the vasodilator and antispasmodic drugs papaverine and emetine. In addition to naturally occurring isoquinolines, synthetic analogs have also shown significant biological activity.

: Fluorinated compounds; Fluorinated compounds refers to organic or inorganic compounds containing fluorine.