製品名:N3-C2-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 3-azidopropanoate

CAS番号:850180-76-6
分子式:C7H8N4O4
純度:95%+
カタログ番号:CM339192
分子量:212.17

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CM339192-100mg in stock ƎȐư
CM339192-500mg 1-2 Weeks ŵȡŵŵ

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製品詳細

CAS番号:850180-76-6
分子式:C7H8N4O4
融点:-
SMILESコード:O=C(ON1C(CCC1=O)=O)CCN=[N+]=[N-]
密度:
カタログ番号:CM339192
分子量:212.17
沸点:
MDL番号:
保管方法:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Azides
Azides are used in click chemistry, such as copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC),and strain-promoted [3+2] azide-alkyne cycloaddition reaction (SPAAC).
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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