製品名:5-Cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride

IUPAC Name:5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride

CAS番号:861409-65-6
分子式:C11H8ClF2N3O
純度:95%+
カタログ番号:CM271891
分子量:271.65

包装単位 有効在庫 価格(USD) 数量
CM271891-1g 1-2 Weeks ħǙħ
CM271891-5g 1-2 Weeks ŤƈŤ

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製品詳細

CAS番号:861409-65-6
分子式:C11H8ClF2N3O
融点:-
SMILESコード:O=C(Cl)C1=NN2C(C(F)F)=CC(C3CC3)=NC2=C1
密度:
カタログ番号:CM271891
分子量:271.65
沸点:
MDL番号:MFCD03422915
保管方法:

Category Infos

Pyrazolopyrimidines
Pyrazolopyrimidine scaffolds are one of the most important heterocyclic compounds in drug discovery. This scaffold has various biological activities, among which anticancer is an important one.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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