製品名:Fmoc-3VVD-OH

IUPAC Name:(3R,4S,5S)-4-[(2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoic acid

CAS番号:863971-44-2
分子式:C36H51N3O7
純度:95%+
カタログ番号:CM339087
分子量:637.82

包装単位 有効在庫 価格(USD) 数量
CM339087-100mg in stock ǸŌǪ
CM339087-250mg in stock ƚŌǸ
CM339087-1g in stock Ůƈƚ
CM339087-5g 1-2 Weeks ǸǙƈľ
CM339087-10g 3-4 Weeks ƚƈľƚ

研究開発用専用.

問い合わせフォーム

   refresh    

製品詳細

CAS番号:863971-44-2
分子式:C36H51N3O7
融点:-
SMILESコード:CN([C@H]([C@H](OC)CC(O)=O)[C@@H](C)CC)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)=O
密度:
カタログ番号:CM339087
分子量:637.82
沸点:
MDL番号:
保管方法:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
Peptide linkers
Peptide linkers belong to protease-sensitivity linkers (also called enzymatically cleavable linkers) that have gained significant attention in ADC development due to their superior plasma stability and controled payload release mechanism.