Furan is a cyclic flammable liquid compound C4H4O that is obtained from wood oils of pines or made synthetically and is used especially in organic synthesis. Furan is aromatic because a pair of lone pair electrons of the oxygen atom in its molecule forms a large π bond in the plane of the conjugated orbital, making a total of 6 electrons in the plane of the conjugated plane, conforming to the 4n+2 structure. Aromaticity makes furan have the property of easy substitution and difficult addition. The other lone pair of electrons in oxygen stretches out. The oxygen atom itself conforms to sp2 hybridization. Due to the presence of the aromatic ring, the chemical behavior of furan is not very similar to that of other unsaturated heterocycles. The oxygen in the aromatic ring has an electron-donating effect, so the electrophilic substitution reactivity of furan is stronger than that of benzene.
Furan | C4H4O | Where to Buy Furans-Chemenu
Furane | Furanes | Furfuran | Furan | C4H4O | Furan Synthesis | Where to Buy Furans
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Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Benzodioxanes are a class of isomeric compounds with the molecular formula C8H8O2. The three isomers of benzodioxane are 1,2-benzodioxane, 1,3-benzodioxane and 1,4-benzodioxane. 1,4-Benzodioxane has long been a versatile template widely used to design molecules with diverse biological activities. Its use spans past decades in medicinal chemistry to today, involving many drug discovery strategies, not excluding the most advanced ones. 1,4-Benzodioxane derivatives have been described as agonists and antagonists of nicotinic, alpha-adrenergic and 5-HT receptor subtypes. 1,4-Benzodioxane derivatives have been also reported as antitumor and antibacterial agents.
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