製品名:4-Aminophenylboronic acid

IUPAC Name:(4-aminophenyl)boronic acid

CAS番号:89415-43-0
分子式:C6H8BNO2
純度:95%+
カタログ番号:CM143205
分子量:136.95

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製品詳細

CAS番号:89415-43-0
分子式:C6H8BNO2
融点:-
SMILESコード:OB(C1=CC=C(N)C=C1)O
密度:
カタログ番号:CM143205
分子量:136.95
沸点:
MDL番号:MFCD01074656
保管方法:

Category Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos

BMF-219
Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.