cas 896464-16-7|| where to buy tert-butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate

製品名:tert-butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate

IUPAC Name:tert-butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate

: CAS番号：896464-16-7; 分子式：C12H22N2O2; 純度：97%

: カタログ番号：CM100746; 分子量：226.32

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CM100746-5g	in stock	ƀŴǕ
CM100746-25g	in stock	ǧȬȬ
CM100746-100g	in stock	ƀƱƙȁ

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製品詳細

: CAS番号:896464-16-7; 分子式:C12H22N2O2; 融点:-; SMILESコード:CC(C)(C)OC(=O)N1CCC2(CNC2)CC1; 密度:1.08g/cm3

: カタログ番号:CM100746; 分子量:226.32; 沸点:319.4°C at 760 mmHg; MDL番号:MFCD09839640; 保管方法:Store at 2-8°C.

Category Infos

: Piperidines; Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.; Piperidine,Piperidine Price; if you want to know the latest news about piperidine and piperidine price, please come to our website and get a quote for free.

: Azetidines; Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.; Where to buy Azetidines; Where to buy ADC-Cytotoxins? Chemenu Provide Azetidines with high quality and competitive price. Contact us Now.

Column Infos

: Spiro Compounds; A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.

: Revumenib; Syndax announced pivotal AUGMENT-101 trial of Revumenib in relapsed/refractory KMT2Ar acute leukemia met primary endpoint and stopped early for efficacy following protocol-defined interim analysis. Revumenib is a potent, selective, small molecule inhibitor of the menin-KMT2A binding interaction that is being developed for the treatment of KMT2A-rearranged, also known as mixed lineage leukemia rearranged or MLLr, acute leukemias including ALL and AML, and NPM1-mutant AML.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.

: DSP-5336; Sumitomo Pharma announces that DSP-5336 has received FDA Fast Track Designation for the treatment of relapsed or refractory acute myeloid leukemia (AML) with a KMT2A rearrangement, also known as, mixed lineage leukemia rearrangement (MLLr) or nucleophosmin mutation (NPM1m). Menin serves as a tumor suppressor in endocrine glands. Novel menin inhibitors are novel targeted agents in clinical studies targeting genetically defined subsets of acute leukemia.
DSP-5336 is an investigational menin-MLL interaction inhibitor. DSP-5336 has been granted Orphan Drug Designation in acute myeloid leukemia, and Fast Track Designation in relapsed or refractory acute myeloid leukemia with MLLr or NPM1m.

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