CAS 89793-12-4;ethyl 2-chloropyrimidine-5-carboxylate

製品名:ethyl 2-chloropyrimidine-5-carboxylate

IUPAC Name:ethyl 2-chloropyrimidine-5-carboxylate

包装単位	有効在庫	価格（USD）
CM108980-25g	in stock	ħƚ
CM108980-100g	in stock	Žƴǟ
CM108980-500g	in stock	řǎřƚ

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: CAS番号:89793-12-4; 分子式:C7H7ClN2O2; 融点:-; SMILESコード:O=C(C1=CN=C(Cl)N=C1)OCC; 密度:

: カタログ番号:CM108980; 分子量:186.6; 沸点:314.2°C at 760 mmHg; MDL番号:MFCD09863164; 保管方法:Keep in a tight container and store at ambient temperature

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: Avapritinib; Blueprint Medicines announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.  AYVAKYT was designed to potently and selectively target KIT D816V, the primary underlying driver of the disease.
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