Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
The S1P1 receptor, a protein that plays a pivotal role in regulating immune response, interacts with S1P, a plasma lipid mediator. Remarkably, S1P regulates an array of physiological phenomena such as angiogenesis, inflammation, immunity, cell motility, and neurotransmitter release.
Enter Cenerimod, a novel, potent, and selective S1P1 receptor modulator featuring unique signaling properties, while notably negating broncho‐ and vasoconstrictor effects. Hence, Cenerimod stands as a promising candidate in the quest for improved S1P1 receptor modulators.