製品名:{imidazo[1,2-a]pyridin-6-yl}boronic acid

IUPAC Name:{imidazo[1,2-a]pyridin-6-yl}boronic acid

CAS番号:913835-63-9
分子式:C7H7BN2O2
純度:95%+
カタログ番号:CM109030
分子量:161.96

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製品詳細

CAS番号:913835-63-9
分子式:C7H7BN2O2
融点:-
SMILESコード:OB(C1=CN2C(C=C1)=NC=C2)O
密度:
カタログ番号:CM109030
分子量:161.96
沸点:
MDL番号:MFCD06739225
保管方法:-20°C

Category Infos

Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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