cas 916420-27-4|| where to buy tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

製品名:tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

IUPAC Name:tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

包装単位	有効在庫	価格（USD）
CM104183-5g	in stock	Ǻƅ
CM104183-10g	in stock	ŭƻŭ
CM104183-25g	in stock	ƏƩƏ
CM104183-100g	in stock	œȋǠ

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: CAS番号:916420-27-4; 分子式:C12H15Cl2N3O2; 融点:-; SMILESコード:CC(C)(C)OC(=O)N1CCC2=C(Cl)N=C(Cl)N=C2C1; 密度:

: カタログ番号:CM104183; 分子量:304.17; 沸点:; MDL番号:MFCD09025732; 保管方法:

: Adagrasib; Jan. 10, 2024, EC approves KRAZATI (adagrasib) as a targeted treatment option for patients with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation.
Adagrasib is an orally available, potent, irreversible, small molecule inhibitor of KRAS G12C mutant isoform for the treatment of solid tumours harbouring KRAS G12C oncogenic driver mutation. Adagrasib covalently binds to the mutant cysteine in KRAS G12C and locks the mutant KRAS protein in its inactive state, thereby preventing downstream signalling without affecting wild-type KRAS protein.