製品名:4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

IUPAC Name:4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

CAS番号:944401-71-2
分子式:C11H16BFN2O2
純度:95%
カタログ番号:CM219293
分子量:238.07

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CAS番号:944401-71-2
分子式:C11H16BFN2O2
融点:-
SMILESコード:NC1=NC=C(B2OC(C)(C)C(C)(C)O2)C(F)=C1
密度:
カタログ番号:CM219293
分子量:238.07
沸点:
MDL番号:
保管方法:

Category Infos

Pyridines
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu
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Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Product Overview 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (4F-5TMDPA) is an organic compound that has been used in a variety of scientific applications. It is a versatile molecule that can be used in a variety of different ways, including as a catalyst, an inhibitor, and a fluorescent dye. 4F-5TMDPA has been studied extensively in the laboratory and is being explored for its potential applications in a variety of fields, including biochemistry, physiology, and pharmacology.
Synthesis and Application The synthesis of 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine involves a series of steps that involve the use of several reagents and catalysts. The first step involves the reaction of pyridine-2-carboxylic acid with 4-fluoro-5-bromopyridine in the presence of a base, such as potassium carbonate, to form 4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (4F-5TMD). This reaction is followed by the reaction of 4F-5TMD with an amine, such as ethylamine, to form 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine. 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine has been used in a variety of scientific research applications. It has been used as a catalyst in the synthesis of heterocyclic compounds, such as pyrrolidines, piperidines, and quinolines. It has also been used as an inhibitor in the synthesis of polymers, such as polyesters, polyamides, and polyurethanes. In addition, 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine has been used as a fluorescent dye in the detection of proteins, nucleic acids, and other biomolecules.
Future Directions The potential future directions for 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine include further exploration of its biochemical and physiological effects, its potential applications in drug development, and its potential use in the detection of proteins and other biomolecules. In addition, further research may be conducted to explore the mechanism of action of 4-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine and to identify new ways to use it in laboratory experiments.