製品名:2,2,2-Trifluoro-N-(6-chloroimidazo-[1,2-b]pyridazin-2-yl)acetamide

IUPAC Name:N-{6-chloroimidazo[1,2-b]pyridazin-2-yl}-2,2,2-trifluoroacetamide

CAS番号:947248-50-2
分子式:C8H4ClF3N4O
純度:95%+
カタログ番号:CM320337
分子量:264.59

包装単位 有効在庫 価格(USD) 数量
CM320337-250mg in stock ƥȯ
CM320337-1g 1-2 Weeks ȖŪŞ
CM320337-5g 1-2 Weeks ȯŪǫ

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製品詳細

CAS番号:947248-50-2
分子式:C8H4ClF3N4O
融点:-
SMILESコード:O=C(NC1=CN2N=C(Cl)C=CC2=N1)C(F)(F)F
密度:
カタログ番号:CM320337
分子量:264.59
沸点:
MDL番号:MFCD21642045
保管方法:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.

Column Infos

Fluorinated compounds
Fluorinated compounds refers to organic or inorganic compounds containing fluorine.

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