cas 98604-89-8|| where to buy Bis-SS-C3-sulfo-NHS ester

製品名:Bis-SS-C3-sulfo-NHS ester

IUPAC Name:1-{[4-({4-[(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy]-4-oxobutyl}disulfanyl)butanoyl]oxy}-2,5-dioxopyrrolidine-3-sulfonic acid

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: CAS番号:98604-89-8; 分子式:C16H20N2O14S4; 融点:-; SMILESコード:O=S(C(C1)C(N(OC(CCCSSCCCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O)=O)C1=O)=O)(O)=O; 密度:

: ADC-Linkers; The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.

: Cleavable linkers; Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.

: Disulfides/Thiols; In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.