製品名:2-(trans-4-Hydroxycyclohexyl)isoindoline-1,3-dione

IUPAC Name:2-[(1r,4r)-4-hydroxycyclohexyl]-2,3-dihydro-1H-isoindole-1,3-dione

CAS番号:99337-98-1
分子式:C14H15NO3
純度:95%+
カタログ番号:CM148256
分子量:245.28

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製品詳細

CAS番号:99337-98-1
分子式:C14H15NO3
融点:-
SMILESコード:O=C1N([C@H]2CC[C@H](O)CC2)C(C3=C1C=CC=C3)=O
密度:
カタログ番号:CM148256
分子量:245.28
沸点:410°C at 760 mmHg
MDL番号:
保管方法:Store at 2-8°C.

Category Infos

Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

Column Infos

Cadisegliatin
vTv Therapeutics announces FDA submission for first phase 3 study of Cadisegliatin in patients with type 1 diabetes. Cadisegliatin (TTP399) is developed as an adjunctive therapy to insulin for the treatment of type 1 diabetes, and the phase 3 trial evaluates its safety and efficacy.
Glucokinase (GK) is mainly concentrated in liver cells, and involved in the regulation of glucose metabolism. Cadisegliatin (TTP399) is a liver-selective glucosekinase activator with a mechanism of action different from that of antidiabetic drugs. It binds to the allosteric site of GK and restores innate glucose-regulating capacity of the liver, not disrupting the interaction between GK and GKRP. Cadisegliatin previously received a Breakthrough Therapy designation from the U.S. FDA.

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